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Pantethine is a highly absorbable and biologically active form of
pantopthenic acid (vitamin B-5). Pantethine forms the reactive
component of Coenyme A (CoA) and the acyl-carrier protein (ACP). CoA
and ACP are extensively involved in carbohydrate, lipid, and amino
acid metabolism. It is also essential in producing, transporting,
and releasing energy from fats and has been reported to lower blood
levels of cholesterol and triglycerides.
Some studies
indicate that pantethine may favorably affect lipids and protect
against forms of cardio muscular disease. Additionally, it has been
shown to protect against a number of toxins, including alcohol.
Preliminary research leads researchers to believe that pantethine
may influence various central nervous system and adrenal junctions,
but no useful conclusions can yet be drawn from these early
investigations. While it has been suggested in some published
articles that pantethine supplementation may enhance exercise
performance and inhibits hair loss and graying of hair, there is no
evidence to suggest that either of these claims are
true.
Dosage
While most healthy
people do not require additional amounts of pancreatin, the 10–25 mg
found in some multivitamin supplements might improve levels of
pantothenic acid (pancreatin). Possible lipid-lowering dosage
typically ranges from 600 to 1,200 milligrams daily, taken in
divided doses.
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