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Cranberry is a relatively small, red berry which grows
on low-hanging vines in temperate zones in many regions of the
United States and other parts of the world. Cranberry is a member of
the same family of plants as bilberry and blueberry. Cranberry can
be taken as a juice, the whole berry, or from an extract. For
maximum health benefit, cranberry juice should be
unsweetened.
The active ingredients in cranberry include
chemical compounds called proanthocyanidins. Proanthocyanidins are
potent antioxidants that appear to be able to decrease bacterial
adherence to the bladder epithelium cells. The main benefit of this
action is that bacteria have less likelihood of grouping together to
cause bladder infection, urinary track infections and other related
conditions.
Suggested Health Benefits of Associated
with Cranberries
- Urinary Tract Infections - Many people take cranberry
supplements to prevent urinary tract infections caused by
bacteria. Specifically, the proanthocyanidins found in cranberry
appear to block the adhesive strands on the E. coli bacteria from
sticking to a surface whereby inhibiting their ability to stick to
the cell walls of the uterus and bladder.
- Reduction of Dental Plaque - It is believed that
cranberry juice can inhibit the aggregation of bacteria that cause
dental plaque.
- Anti-Cancer Activity - Based on evaluation of several
vitro screening tests, it has been suggested that the
proanthocyanidin compounds found in cranberry may exhibit
potential anti-carcinogenic activity.
- Heart Disease - Cranberry extract has been shown to
inhibit low density lipoprotein oxidation. Since this process is
believed to be part of what can cause heart disease, and
prevention of oxidation through cranberry supplementation can
potentially reduce the risk of heart disease.
- Kidney stones - Some medical professionals and
specialists believe that quinic acid abundant in cranberry may
help to prevent the development of kidney
stones.
Recommended
Dosage
One 400 mg capsule of concentrated cranberry
juice extract can be taken two times per day. Several 16-ounce (500
ml) glasses of high-quality unsweetened cranberry juice from
concentrate each day approximate the effect of a capsule. If using
cranberry tincture 1/2 to 1 teaspoon should be taken three times per
day.
Side Effects
No major side
effects have been reported.
Supporting
Literature
Zafriri D, Ofek I, Adar R, et al.
Inhibitory activity of cranberry juice on adherence of type 1 and
type P fimbriated Escherichia coli to eucaryotic cells. Antimicrob
Agents Chemother 1989;33:92–98. Schlager TA. Effect of cranberry
juice on bacteriuria in children with neurogenic bladder. J Pediatr.
1999;135:698-702. Schmidt DR, Sobota AE. An examination of the
anti-adherence activity of cranberry juice on urinary and nonurinary
bacterial isolates. Microbios. 1988;55 (224-225):173-181. Howell
AB, Vorsa N, Der Maderosian A. Inhibition of the adherence of
P-fimbriated Escherichia coli to uroepithelial—all surfaces by
proanthocyanidin extracts from cranberries. New Engl J Med
1998;339:1005–1006. Brown DJ. Herbal Prescriptions for Better
Health. Rocklin, CA: Prima Publishing, 1996, 57–61. Rotblatt M,
Ziment I. Evidence-Based Herbal Medicine. Philadelphia, PA: Hanley
& Belfus, Inc; 2002:145-147.
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