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Coenzyme Q-10 (CO Q10) is a chemical found naturally in the human
body. Small amounts of it are obtained from eating meat and seafood,
but the majority is created directly by the body. Although nearly
all body cells make it, coenzyme Q-10 concentrates in the muscles
and in the heart, kidneys, liver, and pancreas. Approximate 50
percent of the body’s stores of coenzyme Q-10 are found in the
mitochondria of the cells. Mitochondria are components of cells that
transform dietary carbohydrates into energy. While coenzyme Q-10 is
involved in strengthening body membranes, its main function is to
carry electrons that are needed in the energy generation
process.
For individuals suffering from congestive heart
failure, irregular heartbeat, or angina, Coenzyme Q10 may ease
symptoms and improve cardiac function. Some doctors also recommend
it after heart surgery to speed recovery with a minimum of permanent
damage. Some health practitioners contend that Coenzyme Q10 can
stave off hardening of the arteries by discouraging the build-up of
plaque on artery walls. Others suggest that it can boost the immune
system, helping to prevent the spread of cancer. It has also been
recommended for a host of additional disorders ranging from high
blood pressure, diabetes, allergies, and fatigue to Alzheimer's
disease, Bell's palsy, Huntington's disease, Ménière's disease,
muscular dystrophy, and deterioration of the retina.
CoQ10 is
a also powerful antioxidant that protects the body from free
radicals and helps preserve vitamin E, the major antioxidant of cell
membranes and blood cholesterol. Coenzyme Q10 supplementation has
been investigated as a way to improve physical endurance because of
its effect on energy production; however, most research shows that
CoQ10 does not improve athletic performance.
Dosage
and Administration
Coenzyme Q10 is available in
capsule, tablet, softgel (gel cap), and chewable form. To improve
its absorption, it can be taken with some type of oil (olive oil is
recommended) or fat (peanut butter, for example). It is also best to
take your dosage with meals.
Dosage recommendations range
from 30 milligrams to 400 milligrams daily, generally increasing
with the severity of the problem. Large daily doses are typically
divided into 2 or 3 smaller doses (for example, one 60 milligram
tablet taken 2 times a day instead of a single 120 milligram tablet
taken once). If you are taking the enzyme for a heart condition, it
may be 2 to 8 weeks before you notice any benefit, and you will need
to continue taking the product to maintain any improvement.
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