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Hemlock (Conium maculatum)
is POISON! Hemlock is a member of the great order Umbelliferae,
the same family of plants to which the parsley, fennel, parsnip
and carrot belong.
The Ancients were familiar with the plant,
which is mentioned in early Greek literature, and fully
recognized its poisonous nature. The juice of hemlock was
frequently administered to criminals, and this was the fatal
poison which Socrates was condemned to drink.
Hemlock was used in Anglo-Saxon medicine, and
is mentioned as early as the tenth century. The name Hemlock is
derived from the Anglo-Saxon words hem (border, shore) and
leác (leek or plant). Another authority derives the
British name 'hemlock' from the Anglo-Saxon word healm (straw),
from which the word 'haulm' is derived.
The use of Hemlock in modern medicine is due
chiefly to the recommendation of Storch, of Vienna, since when
(1760) the plant has been much employed, though it has lost some
of its reputation owing to the uncertain action of the
preparations made from it.
Hemlock is a tall, much branched and gracefully
growing plant, with elegantly-cut foliage and white flowers.
Country people very generally call by the name of Hemlock many
species of umbelliferous plants, but the real Hemlock may be
distinguished by its slender growth, perfectly smooth stem which
is marked with red, and its finely-divided leaves which are also
smooth.
The entire plant has a bitter taste and
possesses a disagreeable mousy odor, which is especially
noticeable when bruised. When dry, the odor is still
disagreeable, but not so pronounced as in the fresh plant. The
seeds or fruits have very marked odor or taste, but when rubbed
with a solution of potassium bi-oxide, the same disagreeable
mouse-like odor is produced.
The poisonous property occurs in all parts of
the plant, though it is stated to be less strong in the root.
Poisoning has occurred from eating the leaves for parsley, the
roots for parsnips and the seeds in mistake for anise seeds. Many
children, too, have suffered by using whistles made from the
hollow stems of the Hemlock, which should be extirpated from
meadows and pastures since many domestic animals have been killed
by eating it, though goats are said to eat it with impunity.
By far the most important constituent of
hemlock leaves is the alkaloid Coniine, of which they may
contain, when collected at the proper time, as much as 2.77% the
average being 1.65%. When pure, Coniine is a volatile, colorless,
oily liquid, strongly alkaline, with poisonous properties and
having a bitter taste and a disagreeable, penetrating, mouse-like
odor. There are also present the alkaloids, Methyl-coniine,
Conhydrine, Pseudoconhydrine, Ethyl piperidine, mucilage, a fixed
oil and 12% of ash.
Hemlock fruits have essentially the same active
constituents, but yield a greater portion of Coniine than the
leaves. As a medicine, Conium is sedative and antispasmodic, and
in sufficient doses acts as a paralyzer to the centers of motion.
In its action it is, therefore, directly antagonistic to that of
Strychnine, and hence it has been recommended as an antidote to
Strychnine poisoning, and in other poisons of the same class, and
in tetanus, hydrophobia, etc. (In medieval days, Hemlock mixed
with betony and fennel seed was considered a cure for the bite of
a mad dog.)
On account of its peculiar sedative action on
the motor centers, Hemlock juice (Succus conii) is
prescribed as a remedy in cases of undue nervous motor
excitability, such as teething in children, epilepsy from
dentition. cramp, in the early stages of paralysis agitans, in
spasms of the larynx and gullet, in acute mania, etc. As an
inhalation it is said to relieve cough in bronchitis,
whooping-cough, asthma, etc.
The drug has to be administered with care, as
narcotic poisoning may result from internal use, and overdoses
produce paralysis. In poisonous doses it produces complete
paralysis with loss of speech, the respiratory function is at
first depressed and ultimately ceases altogether and death
results from asphyxia. The mind remains unaffected to the last.
In the account of the death of Socrates, reference is made to
loss of sensation as one of the prominent symptoms of his
poisoning, but the dominant action is on the motor system. It is
placed in Table II of the Poison Schedule.
Hemlock was formerly believed to exercise an
alterative effect in scrofulous disorders. Both the Greek and
Arabian physicians were in the practice of using it for the cure
of indolent tumors, swellings and pains of the joints, as well as
for affections of the skin. Among the moderns Baron Storch was
the first to call the attention of medical men to its use, both
externally and internally, for the cure of cancerous and other
ulcers, and in the form of a poultice or ointment it has been
found a very valuable application to relieve pain in these cases.
In the case of poisoning by Hemlock, the
antidotes are tannic acid, stimulants and coffee, emetics of
zinc, or mustard and castor oil, and, if necessary, artificial
respiration. It is essential to keep up the temperature of the
body. Like many other poisonous plants, when cut and dried,
Hemlock loses much of its poisonous properties, which are
volatile and easily dissipated. Cooking destroys it. Its
disagreeable odor has prevented its fatal use as a vegetable in
the raw state.
Larks and quails are said to eat Hemlock with
impunity, but their flesh becomes so impregnated with the poison
that they are poisonous as food. Thrushes eat the fruits with
impunity, but ducks have been poisoned by them.
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