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Garlic is a member of
the lily family closely related to onions and leeks. Garlic has
been cultivated for thousands of years for its therapeutic
benefits by the ancient Egyptians, Greeks, Romans, Indians and
Chinese. Primary use of Garlic was as a treatment for tumors,
headaches, weakness and fatigue, wounds, sores and infections. It
was regarded as a physically enhancing tonic, and was used by the
first Olympic athletes as an energizer.
The scientific community has long respected
Garlic as a plant possessing impressive therapeutic activity.
Louis Pasteur first demonstrated Garlic's anti-bacterial
properties in 1858, and later Albert Schweitzer used Garlic to
treat amoebic dysentery. More recently, researchers have
demonstrated that Garlic helps protect against heart disease and
cancer, and possess remarkable antibiotic effects. Garlic juice
and its constituents can slow, or kill, more than sixty fungi and
twenty types of bacteria, including some of the most virulent
known to man.
Researchers really began studying Garlic after results of an epidemiological study were published about ten years ago. The long-term study compared three groups of vegetarians in India who:
The mean fasting cholesterol levels for those
ingesting large amounts of Garlic was 159 mg/100 ml of serum. For
those ingesting moderate amounts, the level was 172 mg/100 ml of
serum, and those ingesting no Garlic serum cholesterol levels
were 208 mg/100 ml of serum.
The diet of all three groups was virtually
identical except for the difference in Garlic intake. Researchers
also reported that those who abstained completely from Garlic and
onions had blood that clotted more quickly than did those who
consumed Garlic and onions.
In a another study, two sets of patients
suffering with coronary-artery disease were enlisted in a
ten-month study. One group got Garlic supplements while the other
group did not. Those who received Garlic had steadily declining
levels of lipoproteins associated with heart disease, while the
group that didn't get Garlic showed no decline in these
lipoproteins.
Researchers concluded: "The positive
reports appear to be overwhelming. The reviewers were surprised
by the scarcity of negative reports." Scientists also
reviewed a variety of animal studies, many well controlled, in
which Garlic clearly exhibited a statistically significant
lowering effect on cholesterol. The effect in most studies was
found to be "dose-related," meaning that the higher the
daily dose of Garlic, the greater the reduction in cholesterol.
Various sulfur compounds contained in Garlic
appear to account for this favorable effect on cardiovascular
health. Some of these are known to have significant impact on the
biosynthesis of fatty acids, cholesterol, triglycerides and
phospholipids. Ajoene, a Garlic compound, has a potent
anti-clotting effect and appears to be the crucial component in a
number of Garlic's therapeutic actions.
Other compounds in Garlic have exhibited
anti-tumor effects in animals. Epidemiologic studies in China
show that eating a lot of Garlic can protect against stomach
cancer. Those who ate an average of seven Garlic cloves a day had
an incidence of gastric cancer ten times lower than those who
rarely, if ever, ate Garlic. The Garlic, in this case, seemed to
work, at least in part, by preventing dietary nitrites from
converting to cancer-causing nitrosamines.
Animal cancer research with Garlic is
impressive. Researchers recently proved that a Garlic compound,
diallyl sulfide, given to mice prior to exposure to a
colon-cancer-inducing agent, has a potent protective effect. The
Garlic-treated animals got 75 percent fewer tumors than control
animals not given Garlic. In a similar experiment, Garlic
completely protected mice against esophageal cancer. In other
animal research, sulfur compounds of Garlic have inhibited
stomach and skin cancers.
These compounds seem to work by enabling the
liver to detoxify cancer causing chemicals before they can do
harm. Additionally, Garlic contains bioflavonoids and
antioxidants, both known anti-carcinogens. Allicin is another of
the active sulfur compounds in Garlic, and is the substance that
gives garlic its antibiotic qualities.
There is one study which suggests that high
doses of Garlic might also increase physical endurance.
Researchers wanted to see if Garlic could protect heart muscles
against a toxic drug. They injected rats with the heart-damaging
drug isoproterenol. One group of these rats got Garlic in their
diet for a week prior to the injection with the drug. Another
group got the drug, too, but no Garlic. The Garlic-fed rats
withstood the effects of the drug far better than the rats that
didn't get Garlic. The Garlic-protected rats showed their greater
physical endurance by swimming an average of 840 seconds before
and 560 seconds after the drug injection. The rats that didn't
get Garlic could swim only an average of 480 seconds before and
only 78 seconds after injection. At autopsy, far fewer lesions
were found in the heart muscles of the Garlic-supplemented rats
than in the muscles of the control rats.
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